a) Classification of Inorganic Pharmaceuticals based on their applications, therapeutic classes with example and uses.
b) Quality control and tests for purity, qualitative
tests for anions and cations.
c) Limit test for Arsenic, heavy metals, Mercury, lead,
iron, chloride and Sulphate and Pharmacopoeia Standards.
Note: following units all the compounds are of IP
except which are mentioned as BP.
Definition,
Preparation, Properties, Assay methods, Limit tests and Uses
a) Gastro – intestinal agents:
(i) Acidifiers and Antacids: IP: Dilute hydrochloric acid,
sodium acid phosphate, sodium bicarbonate, sodium citrate, Potassium citrate,
Aluminum hydroxide gel, Dried Aluminum hydroxide gel, Magnesium oxide
(Magnesia), Magnesium-hydroxide mixture, Magnesium carbonate, Magnesium
trisilicate, Calcium carbonate.
(ii) Adsorbents and Related Drugs: Light kaolin, Heavy
kaolin, Activated charcoal.
(iii) Laxatives: Magnesium Sulphate and sodium
phosphate.
b)
Electrolytes: Sodium, Potassium and
Calcium replenishers.
(i)
Sodium and Potassium replenishers: Sodium chloride (compound, injection and
Ringer solution), Sodium chloride and dextrose injection, Potassium chloride
and oral electrolytes.
(ii)
Calcium Replenishers: Calcium chloride, Calcium gluconate, Dibasic calcium
phosphate.
(c) Acid base Regulators: Sodium bicarbonate, sodium lactate injection, sodium
citrate / Potassium citrate, sodium acetate, Ammonium chloride, Ammonium
chloride injection.
(d) Dialysis fluids: Haemodialysis
fluids and intraperitoneal dialysis fluids.
Definition,
Preparation, Properties, Assay methods, Limit tests and Uses
(a) Mineral Nutrients:
i. Haematinics: Ferrous Sulphate, Ferrous fumarate,
Ferrous gluconate, Ferric ammonium citrate, iron and dextrose injection.
ii. Metallics: Copper, Manganese and Zinc compounds (zinc
chloride);
iii. Phosphates: Sodium acid phosphate and Sodium
phosphate,
iv. Halogens: Iodine and Iodides or fluorides.
(b)
Pharmaceutical aids:
i. Adsorbents &
Absorbents: Activated charcoal, aluminium sulphate, aluminium phosphate.
ii. Antioxidants: Sodium Sulphite, sodium bisulphate and
sodium metabisulphite.
iii. Desiccants: Silica gel.
iv. Excipients: Dicalcium & Tricalcium Phosphate,
Magnesium stearate, Talc & ppted chalk.
v. Suspending agents: Bentonite, colloidal silica, aluminium
stearate,.
vi. Colourants: Titanium oxide, ferric oxide
vii. Solvent and Vehicle: Purified water
Definition, Preparation, Properties, Assay methods,
Limit tests and Uses
i. Expectorants:
of Ammonium chloride, Potassium Iodide.
ii. Emetics: Potassium antimony tartarate, copper Sulphate, Zinc
Sulphate.
iii. Antidotes:
Sodium thiosulphate, sodium thiosulphate injection , sodium nitrite.
iv. Inhalants:
Oxygen, Nitrous oxide, dilute solution of ammonia (BP), Ammonium carbonate
(BP).
Definition,
Preparation, Properties, Assay methods, Limit tests and Uses
(a) Topical agents:
i. Astringents: ZnSO4, Zinc Oxide, Calcium Hydroxide,
CuSO4 and
Bismuth subcarbonate.
ii. Topical protectants: Zinc oxide, Calamine, Zinc
stearate, Talc, Titanium-dioxide, Heavy kaolin and Light kaolin
iii. Silicone
polymers: Activated Dimethicone.
iv. Anti
infectives: Hydrogen peroxide, Potassium permanganate, Silver Nitrate (Silver protein), Iodine, (solutions,
povidone – iodine), boric acid, zinc – undecylenate, Mercury compounds (Yellow
mercuric oxide, Ammoniated Mercury). Sulphur, Selenium sulphide.
(b) Dental products:
i. Fluorides: Sodium fluoride, Sodium Monofluorophosphate
and stannous fluoride.
ii. Oral antiseptics and Astringents: Hydrogen peroxide,
Sodium peroxide (BP), Magnesium peroxide, Zinc peroxide and Mouth washes
iii. Dentifrices: Calcium carbonate, dibasic calcium
phosphate, calcium phosphate, sodium metaphosphate and strontium chloride.
iv. Cements and Fillers: Zinc oxide.
(c) Other Medicinal agents:
i. Internal parasiticides: Sodium Antimony Gluconate
ii. Anti-neoplastic agents: Cisplatin.
iii. Sedative-hypnotics: Potassium bromide
iv. Anti-depressants: Lithium carbonate
v. Anti-rheumatic agents: Sodium aurothiomalate
vi. Anti-thyroid agents: Potassium perchlorate
vii. Diagnostic agent: Barium Sulphate
viii. Surgical aid: Plaster of Paris