Computation
of analytical results - Significant figures, Concept of error, precision,
accuracy, specificity, sensitivity, detection limit, linearity and range,
ruggedness, standard deviation Rejection of doubtful values with special
reference to volumetric and gravimetric analysis. Calibration of analytical
equipment.
Fundamentals
of volumetric analysis, methods of expressing concentration, primary and
secondary standards.
Physico-chemical
concepts required for analysis such as electrolytic dissociation, Modem theory
of acids, bases and salts - Bronstead - Lowry theory, Lewis electronic theory;
chemical equilibrium, pH and buffer action, solubility product, common ion
effect, hydrolysis of salts and amphoteric substances.
Principles
of Neutralization reactions; Theory of indicators and Neutralization
indicators.
Principles
of oxidation-reduction titration's, redox, self-indicators and their use,
reactions in pharmaceutical analysis precipitation.
Principles
of gravimetric analysis - typical methods involving precipitation, coagulation,
digestion, drying procedures, co-precipitation.
Theory
and applications of complexometric titration's, argentometry, iodometry,
potassium iodate, potassium bromate, EDT A, non-aqueous tritrations redox
titration's, ammonium sulphate, titanous chloride. Principles of gas
analysis.
Stoichiometry
of Ionic equations and Solutions: The Mole concept, Measuring of Moles of
Elements and Compounds; Percentage Composition; Emperical and Molecular
Formula; Balancing of Chemical Equations; Some analytical problems and
calculations based on mass balance, limiting reagent theoretical yield and
percentage yield.