Formulations
Excipients
Properties
and selection, Antioxidants, Preservatives, Colouring agents, Flavouring
agents, Sweetening agents, Diluting agents, Vehicles, Surfactants,
Hydrocolloids, Above Adjuvants should be studied with reference to FDA
approvals and Drugs & Cosmetics Rules wherever applicable.
Capsules
Hard
Gelatin Capsules: Advantages, Sizes, Storage, Printing, Formulation, Selection
of sizes, Filling, Sealing, Cleaning and Polishing, Evaluation.
Soft
Gelatin Capsules: Advantages, Applications, Formulation, Manufacture &
Evaluation.
Suspensions
and Emulsions
Suspensions:
Formulation Types; Deffloculated and Flocculated suspensions, Formulation
parameters; Methods of Manufacture and Evaluation.
Emulsions:
Formulation Types, Formulation-parameters, Manufacturing Methods and Selection
of equipment, Evaluation methods including the shelf life, Concepts of Multiple
emulsions.
Tablets
and Tablet Coating
Tablets:
Types & Classes, Advantages and Disadvantages, Challenges in formulation
and manufacture, Excipients in the formulation, Ideal requirements of
Excipients, Granulation methods, Compression Machines, Processing problems in
compression - Capping & Lamination, Picking & Sticking, Mottling,
Weight variation, Hardness variation etc. Evaluation of Tablets.
Tablet
Coating: Coating principles, General equipment, Sugar coating-steps,
Compression coating, Film coating-steps, materials used in film coating,
enteric coating, Film defects, Specialised coating techniques and Quality
Control of Tablets.
Parenterals
and Opthalmic Preparations
Parenterals:
Definition, Classification and Types of Parenterals, Advantages and
limitations, Preparation, Formulation, Containers, Production procedures &
facilities, Environmental and other controls, Filling procedures, Products
requiring Sterile Packing, Evaluation tests, Sterile powders, Emulsions,
Suspensions.
Opthalmic
Preparations: Requirements of Eye ointments, Eye drops, Formulation, Methods of
preparation, containers, Evaluation and quality control.
Aerosols
and Packaging Materials
Aerosols:
Definition, Types, Advantages and Disadvantages; Propellants, General
Formulation, Manufacturing and packing methods - Pharmaceutical
Applications.
Packaging
Materials: Glass, Plastics, Metal and Rubber, their influence on dosage form
stability.